Beyond SAS / GENETICS

The field of statistical genetics has developed considerably over the past five years due to the substantial advances in genomic technology. The volume and the nature of these data create a need for reliable computer software to perform statistical analyses. SAS/GENETICS offers a collection of procedures specifically tailored for genetic data such as ALLELE, HAPLOTYPE, CASECONTROL and FAMILY procedures. This paper highlights the basic features of some of these procedures as we routinely apply them to the analysis of human genetic association studies. We show examples where SAS/GENETICS can be complemented with other SAS/STAT procedures such as LOGISTIC and PHREG to conduct analyses commonly used in human genetic studies. We also compare output results of SAS/GENETICS procedures to those from analogous analyses with SAS/STAT procedures.